WARNINGS Use with caution in the elderly and in patients with prostatic hypertrophy due to the danger of urinary retention. In patients with cardiovascular diseases, especially in hypertensive patients, the use of nasal decongestants must in any case be subjected to the judgment of the doctor from time to time. The prolonged use of vasoconstrictors can alter the normal function of the mucous membrane of the nose and paranasal sinuses, also inducing addiction to the drug. Repeating applications for a long period of time can be harmful. Benzalkonium chloride (BAC) contained as a preservative in the drug nasal drops and nasal spray, especially when used for long periods, can cause swelling of the nasal mucosa. If such a reaction (persistent nasal congestion) is suspected, a BAC-free nasal medicine should be used if possible. If such nasal medications without BAC are not available, another pharmaceutical form should be considered. It can cause bronchospasm. The use, especially if prolonged, of topical products can give rise to sensitization phenomena; in this case it is necessary to interrupt the treatment and, if necessary, to institute a suitable therapy. Rare cases of posterior reversible encephalopathy / reversible cerebral vasoconstriction syndrome have been reported with the use of sympathomimetic drugs, to which naphazoline also belongs. Symptoms reported include sudden onset of severe headache, nausea, vomiting and visual disturbances. Most cases improve or resolve within a few days with appropriate treatment. The use of naphazoline should be discontinued immediately and the physician should be consulted if signs and / or symptoms of posterior reversible encephalopathy / reversible cerebral vasoconstriction syndrome occur. PHARMACOTHERAPEUTIC CATEGORY Nasal decongestants and other topical preparations. STORAGE This medicine does not require any special storage conditions. CONTRAINDICATIONS / SECONDARY EFFECT Hypersensitivity 'to the active substance or to any of the excipients; severe heart disease and high blood pressure; glaucoma; hyperthyroidism; the medicine is contraindicated in children younger than 12 years; do not administer during and in the two weeks following therapy with antidepressant drugs. NAME RINAZINA EXCIPIENTS Nasal drops, 1 mg / ml solution: sodium chloride, disodium edetate, monobasic sodium phosphate dihydrate, concentrated phosphoric acid, benzalkonium chloride, purified water. Nasal spray, 100 mg / 100 ml solution: sodium chloride, disodium edetate, monobasic sodium phosphate dihydrate, concentrated phosphoric acid, benzalkonium chloride, balsamic aroma, purified water SIDE EFFECTS The product can locally determine rebound phenomena of sensitization and congestion of the mucous membranes. For rapid absorption of naphazoline through the inflamed mucous membranes, systemic effects may occur consisting of arterial hypertension, reflex bradycardia, headache, urination disturbances. PREGNANCY AND BREASTFEEDING In pregnancy and lactation, the drug should be used only after consulting your doctor and having evaluated with him the risk / benefit ratio in your case. INDICATIONS Nasal decongestant in acute catarrhal rhinitis and pharyngitis, allergic rhinitis, acute sinusitis. INTERACTIONS The drug can interact with antidepressant drugs. DOSAGE >> Nasal drops. Adults: 2-3 drops in each nostril, 2-3 times a day. >> Nasal spray. Adults: 1-2 sprays in each nostril, 2-3 times a day. Pediatric population: the drug is contraindicated in children under the age of 12 years. Strictly adhere to the recommended doses. A higher dosage of the product even if taken topically and for a short period of time can 'give rise to serious systemic effects. If there is no complete therapeutic response within a few days, consult your doctor; in any case, the treatment should not be continued for more than a week. ACTIVE PRINCIPLES Naphazoline nitrate 1 mg.